STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0L8FPL4Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (611 aa)    
Predicted Functional Partners:
A0A0L8I2J1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.992
A0A0L8HFV4
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.991
A0A0L8I4B3
Uncharacterized protein.
  
 0.985
A0A0L8G0U4
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.979
A0A0L8HJ19
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.979
A0A0L8HLN7
Uncharacterized protein.
  
 
 0.977
A0A0L8IBJ2
Thymidylat_synt domain-containing protein.
    
 0.967
A0A0L8FIV5
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.962
A0A0L8HCL1
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
    
 0.959
A0A0L8GQV5
Uncharacterized protein.
  
 
 0.914
Your Current Organism:
Octopus bimaculoides
NCBI taxonomy Id: 37653
Other names: O. bimaculoides
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.