A0A0L8GV37 protein (Octopus bimaculoides) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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Score

A0A0L8GV37

Uncharacterized protein. (845 aa)

Predicted Functional Partners:

A0A0L8HJ02

0.619

A0A0L8I4U9

0.498

A0A0L8I428

0.473

A0A0L8FVT5

0.455

A0A0L8FJP4

0.452

A0A0L8FKB6

0.452

Your Current Organism:

Octopus bimaculoides

NCBI taxonomy Id: 37653
Other names: O. bimaculoides

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0L8FJP4	A0A0L8GV37	RBD domain-containing protein.	Uncharacterized protein.	0.452
A0A0L8FKB6	A0A0L8GV37	RGS domain-containing protein.	Uncharacterized protein.	0.452
A0A0L8FVT5	A0A0L8GV37	Uncharacterized protein.	Uncharacterized protein.	0.455
A0A0L8GV37	A0A0L8FJP4	Uncharacterized protein.	RBD domain-containing protein.	0.452
A0A0L8GV37	A0A0L8FKB6	Uncharacterized protein.	RGS domain-containing protein.	0.452
A0A0L8GV37	A0A0L8FVT5	Uncharacterized protein.	Uncharacterized protein.	0.455
A0A0L8GV37	A0A0L8HJ02	Uncharacterized protein.	SH3 domain-containing protein.	0.619
A0A0L8GV37	A0A0L8I428	Uncharacterized protein.	Uncharacterized protein.	0.473
A0A0L8GV37	A0A0L8I4U9	Uncharacterized protein.	Tubby-like protein; Belongs to the TUB family.	0.498
A0A0L8HJ02	A0A0L8GV37	SH3 domain-containing protein.	Uncharacterized protein.	0.619
A0A0L8I428	A0A0L8GV37	Uncharacterized protein.	Uncharacterized protein.	0.473
A0A0L8I4U9	A0A0L8GV37	Tubby-like protein; Belongs to the TUB family.	Uncharacterized protein.	0.498

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.83

expected number of edges:

15

PPI enrichment p-value:

0.0417

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 114

1.55

3.35

2.24e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 55

1.78

4.0

1.47e-12

GO:0019843

rRNA binding

7 of 42

1.78

3.3

2.02e-09

GO:0003723

RNA binding

8 of 121

1.38

2.08

2.56e-08

GO:0000049

tRNA binding

4 of 28

1.72

1.74

0.00013

GO:0003676

Nucleic acid binding

9 of 504

0.81

0.76

5.43e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 63

1.72

3.82

8.73e-13

GO:0015935

Small ribosomal subunit

3 of 6

2.26

2.33

3.03e-05

GO:0005622

Intracellular anatomical structure

11 of 1355

0.47

0.41

0.00014

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:23342046

(2013) The genome sequences of Cellulomonas fimi and Cellvibrio gilvus reveal the cellulolytic strategies of two facultative anaerobes, transfer of Cellvibrio gilvus to the genus Cellulomonas, and proposal of Cellulomonas gilvus sp. nov.

3 of 32

1.53

0.95

0.0091

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:162

Ribosome

9 of 43

1.88

4.66

9.85e-14

CL:166

rRNA-binding

7 of 28

1.96

4.23

3.68e-11

CL:169

rRNA-binding

5 of 15

2.08

3.46

3.66e-08

CL:133

Translation, and Protein export

11 of 136

1.47

2.97

9.85e-14

CL:173

mRNA binding, and rRNA-binding

3 of 6

2.26

2.21

5.49e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

sde03010

Ribosome

9 of 53

1.79

4.26

1.58e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 52

1.69

2.92

9.28e-09

GOCC:0022626

Cytosolic ribosome

5 of 29

1.8

2.55

1.03e-06

GOCC:0044391

Ribosomal subunit

5 of 33

1.74

2.44

1.23e-06

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 13

1.92

1.77

0.00024

GOCC:0043229

Intracellular organelle

9 of 280

1.07

1.29

3.19e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 55

1.78

4.11

4.44e-13

KW-0699

rRNA-binding

7 of 39

1.82

3.57

3.82e-10

KW-0820

tRNA-binding

3 of 19

1.76

1.43

0.0010

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