guaA protein (Clostridium algidicarnis) - STRING interaction network

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Score

guaA

Unannotated protein; Catalyzes the synthesis of GMP from XMP. (510 aa)

Predicted Functional Partners:

guaB

0.999

rplK

0.999

argS

0.999

BD821_10936

0.994

xpt

0.993

BD821_101186

0.993

rph

0.990

apt

0.988

pyrD

0.986

purA

0.984

Your Current Organism:

Clostridium algidicarnis

NCBI taxonomy Id: 37659
Other names: C. algidicarnis, DSM 15099, NCFB 2931, NCIMB 702931

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BD821_101186	BD821_10936	GCA_000703125_02771	GCA_000703125_02248	Unannotated protein.	Unannotated protein.	0.796
BD821_101186	apt	GCA_000703125_02771	GCA_000703125_02707	Unannotated protein.	Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.794
BD821_101186	guaA	GCA_000703125_02771	GCA_000703125_00387	Unannotated protein.	Unannotated protein; Catalyzes the synthesis of GMP from XMP.	0.993
BD821_101186	guaB	GCA_000703125_02771	GCA_000703125_00388	Unannotated protein.	Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.987
BD821_101186	purA	GCA_000703125_02771	GCA_000703125_00969	Unannotated protein.	Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.898
BD821_101186	rph	GCA_000703125_02771	GCA_000703125_00346	Unannotated protein.	Unannotated protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.948
BD821_101186	xpt	GCA_000703125_02771	GCA_000703125_01926	Unannotated protein.	Unannotated protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.794
BD821_10936	BD821_101186	GCA_000703125_02248	GCA_000703125_02771	Unannotated protein.	Unannotated protein.	0.796
BD821_10936	apt	GCA_000703125_02248	GCA_000703125_02707	Unannotated protein.	Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.840
BD821_10936	argS	GCA_000703125_02248	GCA_000703125_02186	Unannotated protein.	Unannotated protein.	0.827
BD821_10936	guaA	GCA_000703125_02248	GCA_000703125_00387	Unannotated protein.	Unannotated protein; Catalyzes the synthesis of GMP from XMP.	0.994
BD821_10936	guaB	GCA_000703125_02248	GCA_000703125_00388	Unannotated protein.	Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.973
BD821_10936	purA	GCA_000703125_02248	GCA_000703125_00969	Unannotated protein.	Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.991
BD821_10936	pyrD	GCA_000703125_02248	GCA_000703125_02637	Unannotated protein.	Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate.	0.875
BD821_10936	rph	GCA_000703125_02248	GCA_000703125_00346	Unannotated protein.	Unannotated protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.	0.569
BD821_10936	xpt	GCA_000703125_02248	GCA_000703125_01926	Unannotated protein.	Unannotated protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.840
apt	BD821_101186	GCA_000703125_02707	GCA_000703125_02771	Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Unannotated protein.	0.794
apt	BD821_10936	GCA_000703125_02707	GCA_000703125_02248	Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Unannotated protein.	0.840
apt	guaA	GCA_000703125_02707	GCA_000703125_00387	Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Unannotated protein; Catalyzes the synthesis of GMP from XMP.	0.988
apt	guaB	GCA_000703125_02707	GCA_000703125_00388	Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.931