node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BD821_101360 | BD821_101364 | GCA_000703125_02591 | GCA_000703125_02587 | Unannotated protein. | Unannotated protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.630 |
BD821_101360 | ffh | GCA_000703125_02591 | GCA_000703125_02586 | Unannotated protein. | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.629 |
BD821_101360 | ftsY | GCA_000703125_02591 | GCA_000703125_02588 | Unannotated protein. | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.698 |
BD821_101360 | smc | GCA_000703125_02591 | GCA_000703125_02589 | Unannotated protein. | Unannotated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.732 |
BD821_101364 | BD821_101360 | GCA_000703125_02587 | GCA_000703125_02591 | Unannotated protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Unannotated protein. | 0.630 |
BD821_101364 | ffh | GCA_000703125_02587 | GCA_000703125_02586 | Unannotated protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.975 |
BD821_101364 | ftsY | GCA_000703125_02587 | GCA_000703125_02588 | Unannotated protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.785 |
BD821_101364 | guaA | GCA_000703125_02587 | GCA_000703125_00387 | Unannotated protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.600 |
BD821_101364 | smc | GCA_000703125_02587 | GCA_000703125_02589 | Unannotated protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Unannotated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.757 |
cinA | ftsY | GCA_000703125_01371 | GCA_000703125_02588 | Unannotated protein; Belongs to the CinA family. | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.524 |
cinA | guaA | GCA_000703125_01371 | GCA_000703125_00387 | Unannotated protein; Belongs to the CinA family. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.587 |
cinA | guaB | GCA_000703125_01371 | GCA_000703125_00388 | Unannotated protein; Belongs to the CinA family. | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.545 |
cinA | smc | GCA_000703125_01371 | GCA_000703125_02589 | Unannotated protein; Belongs to the CinA family. | Unannotated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.809 |
ffh | BD821_101360 | GCA_000703125_02586 | GCA_000703125_02591 | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Unannotated protein. | 0.629 |
ffh | BD821_101364 | GCA_000703125_02586 | GCA_000703125_02587 | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Unannotated protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.975 |
ffh | ftsY | GCA_000703125_02586 | GCA_000703125_02588 | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.997 |
ffh | guaA | GCA_000703125_02586 | GCA_000703125_00387 | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Unannotated protein; Catalyzes the synthesis of GMP from XMP. | 0.524 |
ffh | guaB | GCA_000703125_02586 | GCA_000703125_00388 | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.478 |
ffh | secF | GCA_000703125_02586 | GCA_000703125_02709 | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.673 |
ffh | smc | GCA_000703125_02586 | GCA_000703125_02589 | Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Unannotated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.833 |