STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OAG73733.1Cobalamin biosynthesis domain-containing protein. (128 aa)    
Predicted Functional Partners:
OAG73732.1
Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.998
OAG73734.1
Cobalamin(vitamin B12) biosynthesis protein Precorrin-6Y C5,15-methyltransferase.
 
 
 0.998
OAG73735.1
Precorrin 6x reductase.
 
 
 0.985
cbiD
cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
 
 0.984
OAG73737.1
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.981
OAG73736.1
precorrin-3B C17-methyltransferase.
 
 
 0.962
cobH
precorrin-8X methylmutase.
 
 
 0.962
OAG73739.1
Cobalamin biosynthesis protein CobG.
 
  
  0.872
OAG74691.1
Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
    
 0.724
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.673
Your Current Organism:
Gluconobacter japonicus
NCBI taxonomy Id: 376620
Other names: BCC 14458, BCC 36733 [[Gluconobacter nephelii]], G. japonicus, Gluconobacter japonicus Malimas et al. 2009 emend. Li et al. 2017, Gluconobacter nephelii, Gluconobacter nephelii Kommanee et al. 2011, LMG 26773 [[Gluconobacter nephelii]], LMG:26773 [[Gluconobacter nephelii]], NBRC 106061 [[Gluconobacter nephelii]], NBRC 3271, PCU 318 [[Gluconobacter nephelii]], PCU:318 [[Gluconobacter nephelii]], strain 7, K. Kondo, strain RBY-1 [[Gluconobacter nephelii]]
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