node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OAG72648.1 | queE | A0J51_02093 | A0J51_01838 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.643 |
OAG73221.1 | OAG73222.1 | A0J51_01836 | A0J51_01837 | ABC transporter ATP-binding protein. | ABC transporter permease. | 0.980 |
OAG73221.1 | OAG73225.1 | A0J51_01836 | A0J51_01840 | ABC transporter ATP-binding protein. | 6-pyruvoyl tetrahydropterin synthase. | 0.536 |
OAG73221.1 | queC | A0J51_01836 | A0J51_01839 | ABC transporter ATP-binding protein. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.536 |
OAG73221.1 | queE | A0J51_01836 | A0J51_01838 | ABC transporter ATP-binding protein. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.536 |
OAG73222.1 | OAG73221.1 | A0J51_01837 | A0J51_01836 | ABC transporter permease. | ABC transporter ATP-binding protein. | 0.980 |
OAG73222.1 | OAG73225.1 | A0J51_01837 | A0J51_01840 | ABC transporter permease. | 6-pyruvoyl tetrahydropterin synthase. | 0.536 |
OAG73222.1 | queC | A0J51_01837 | A0J51_01839 | ABC transporter permease. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.536 |
OAG73222.1 | queE | A0J51_01837 | A0J51_01838 | ABC transporter permease. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.536 |
OAG73225.1 | OAG73221.1 | A0J51_01840 | A0J51_01836 | 6-pyruvoyl tetrahydropterin synthase. | ABC transporter ATP-binding protein. | 0.536 |
OAG73225.1 | OAG73222.1 | A0J51_01840 | A0J51_01837 | 6-pyruvoyl tetrahydropterin synthase. | ABC transporter permease. | 0.536 |
OAG73225.1 | OAG74416.1 | A0J51_01840 | A0J51_00776 | 6-pyruvoyl tetrahydropterin synthase. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.406 |
OAG73225.1 | guaA | A0J51_01840 | A0J51_00350 | 6-pyruvoyl tetrahydropterin synthase. | GMP synthase (glutamine-hydrolyzing). | 0.541 |
OAG73225.1 | queC | A0J51_01840 | A0J51_01839 | 6-pyruvoyl tetrahydropterin synthase. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.990 |
OAG73225.1 | queE | A0J51_01840 | A0J51_01838 | 6-pyruvoyl tetrahydropterin synthase. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
OAG73225.1 | queF | A0J51_01840 | A0J51_01983 | 6-pyruvoyl tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.951 |
OAG73225.1 | tgt | A0J51_01840 | A0J51_00775 | 6-pyruvoyl tetrahydropterin synthase. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.453 |
OAG74416.1 | OAG73225.1 | A0J51_00776 | A0J51_01840 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 6-pyruvoyl tetrahydropterin synthase. | 0.406 |
OAG74416.1 | queC | A0J51_00776 | A0J51_01839 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.539 |
OAG74416.1 | queE | A0J51_00776 | A0J51_01838 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.575 |