STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OAG72065.1Phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (615 aa)    
Predicted Functional Partners:
OAG72066.1
KDPG aldolase.
 
 
 0.996
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.983
OAG71840.1
Glucose-6-phosphate 1-dehydrogenase.
 
 
 0.973
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.944
OAG72881.1
2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.926
OAG72041.1
Branched-chain amino acid aminotransferase.
  
 0.914
OAG73057.1
Carbohydrate kinase.
  
 
 0.913
OAG72954.1
Glutamate synthase.
  
  
 0.912
glk
Glucokinase; Belongs to the bacterial glucokinase family.
 
 
 0.889
OAG73061.1
6-phosphogluconate dehydrogenase.
     
 0.886
Your Current Organism:
Gluconobacter japonicus
NCBI taxonomy Id: 376620
Other names: BCC 14458, BCC 36733 [[Gluconobacter nephelii]], G. japonicus, Gluconobacter japonicus Malimas et al. 2009 emend. Li et al. 2017, Gluconobacter nephelii, Gluconobacter nephelii Kommanee et al. 2011, LMG 26773 [[Gluconobacter nephelii]], LMG:26773 [[Gluconobacter nephelii]], NBRC 106061 [[Gluconobacter nephelii]], NBRC 3271, PCU 318 [[Gluconobacter nephelii]], PCU:318 [[Gluconobacter nephelii]], strain 7, K. Kondo, strain RBY-1 [[Gluconobacter nephelii]]
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.