STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 0.999
trpF
Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
 
 0.999
SFS91580.1
Indole-3-glycerol phosphate synthase.
 
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.991
SFS91612.1
Anthranilate synthase component 2.
 
 0.977
SFS91623.1
Anthranilate synthase component 1.
 
  
 0.956
SFS63725.1
Aspartate kinase.
  
 
 0.910
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 0.886
SFS56272.1
Para-aminobenzoate synthetase component 1.
 
  
 0.872
SFT09314.1
Catechol 2,3-dioxygenase.
   
  0.862
Your Current Organism:
Zhouia amylolytica
NCBI taxonomy Id: 376730
Other names: CGMCC 1.6114, Flavobacteriaceae bacterium HN-171, Flavobacteriaceae bacterium HN-172, Flavobacteriaceae bacterium HN-181, JCM 14016, Z. amylolytica, Zhouia amylolytica Liu et al. 2006, strain HN-171
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