STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFT03688.13-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)    
Predicted Functional Partners:
SFT11260.1
[acyl-carrier-protein] S-malonyltransferase.
 0.961
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
 0.923
SFS74925.1
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.917
SFS55929.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
 0.886
SFS67230.1
caffeoyl-CoA O-methyltransferase.
 
  
 
 0.883
SFT17069.1
Glutamate synthase (ferredoxin).
     
 0.856
SFS42316.1
ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.
   
 0.851
SFS51777.1
3-hydroxyacyl-CoA dehydrogenase.
  
 0.844
fabH
3-oxoacyl-[acyl-carrier-protein] synthase-3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.821
fabH-2
3-oxoacyl-[acyl-carrier-protein] synthase-3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.784
Your Current Organism:
Zhouia amylolytica
NCBI taxonomy Id: 376730
Other names: CGMCC 1.6114, Flavobacteriaceae bacterium HN-171, Flavobacteriaceae bacterium HN-172, Flavobacteriaceae bacterium HN-181, JCM 14016, Z. amylolytica, Zhouia amylolytica Liu et al. 2006, strain HN-171
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.