Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
mscLLarge-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (139 aa)    
Predicted Functional Partners:
ATP_00330
Probable transporter, permease component.
     
 0.564
polA
DNA polymerase I (3'-5' exonuclease and polymerase domain.
     
 0.548
ATP_00295
Cold shock-like protein.
  
  
 0.516
rpsD
SSU ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
  
 0.500
metK
S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family.
  
    0.491
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
     
 0.474
dnaK
Molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family.
     
 0.471
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.469
rpsP
30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
  
 0.454
mdlB
Multidrug efflux pump, ATP-binding and permease protein.
     
 0.450
Your Current Organism:
Phytoplasma mali
NCBI taxonomy Id: 37692
Other names: Apple proliferation mycoplasma-like organism, Apple proliferation phytoplasma, C. Phytoplasma mali, Candidatus Phytoplasma mali
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