| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hflB-5 | oppA | ATP_00464 | ATP_00463 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | ABC-type oligopeptide transport system, periplasmatic component. | 0.705 |
| hflB-5 | rplI | ATP_00464 | ATP_00177 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.636 |
| hflB-5 | rplM | ATP_00464 | ATP_00332 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.632 |
| hflB-5 | rplQ | ATP_00464 | ATP_00368 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L17. | 0.607 |
| hflB-5 | rplS | ATP_00464 | ATP_00440 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.612 |
| hflB-5 | rpsG | ATP_00464 | ATP_00393 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.608 |
| hflB-5 | rpsH | ATP_00464 | ATP_00355 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.606 |
| hflB-5 | rpsI | ATP_00464 | ATP_00333 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.615 |
| hflB-5 | rpsK | ATP_00464 | ATP_00366 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.607 |
| hflB-5 | rpsP | ATP_00464 | ATP_00437 | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.615 |
| oppA | hflB-5 | ATP_00463 | ATP_00464 | ABC-type oligopeptide transport system, periplasmatic component. | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.705 |
| rplI | hflB-5 | ATP_00177 | ATP_00464 | 50S ribosomal protein L9; Binds to the 23S rRNA. | HflB protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.636 |
| rplI | rplM | ATP_00177 | ATP_00332 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.967 |
| rplI | rplQ | ATP_00177 | ATP_00368 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L17. | 0.979 |
| rplI | rplS | ATP_00177 | ATP_00440 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.977 |
| rplI | rpsG | ATP_00177 | ATP_00393 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.970 |
| rplI | rpsH | ATP_00177 | ATP_00355 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.970 |
| rplI | rpsI | ATP_00177 | ATP_00333 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.967 |
| rplI | rpsK | ATP_00177 | ATP_00366 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.967 |
| rplI | rpsP | ATP_00177 | ATP_00437 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.966 |