IW18_08065 protein (Flavobacterium hibernum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Flavobacterium hibernum

NCBI taxonomy Id: 37752
Other names: ACAM 376, ATCC 51468, CIP 105745, DSM 12611, F. hibernum, NCTC 13514

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IW18_08060	IW18_08065	IW18_08060	IW18_08065	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.648
IW18_08060	IW18_08070	IW18_08060	IW18_08070	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.646
IW18_08065	IW18_08060	IW18_08065	IW18_08060	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.648
IW18_08065	IW18_08070	IW18_08065	IW18_08070	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.829
IW18_08065	IW18_14265	IW18_08065	IW18_14265	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.646
IW18_08065	IW18_14275	IW18_08065	IW18_14275	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.756
IW18_08065	IW18_15250	IW18_08065	IW18_15250	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.752
IW18_08065	IW18_15730	IW18_08065	IW18_15730	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.646
IW18_08065	IW18_22005	IW18_08065	IW18_22005	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.803
IW18_08065	fumC	IW18_08065	IW18_02415	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.769
IW18_08065	sdhA	IW18_08065	IW18_14270	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
IW18_08065	sdhA-2	IW18_08065	IW18_15735	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.664
IW18_08070	IW18_08060	IW18_08070	IW18_08060	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.646
IW18_08070	IW18_08065	IW18_08070	IW18_08065	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.829
IW18_14265	IW18_08065	IW18_14265	IW18_08065	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.646
IW18_14265	IW18_14275	IW18_14265	IW18_14275	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
IW18_14265	IW18_15250	IW18_14265	IW18_15250	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.877
IW18_14265	IW18_15730	IW18_14265	IW18_15730	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.634
IW18_14265	IW18_22005	IW18_14265	IW18_22005	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.986
IW18_14265	fumC	IW18_14265	IW18_02415	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.957