STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gyrAUnannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (812 aa)    
Predicted Functional Partners:
DDZ44_10830
Unannotated protein.
 0.999
GCA_001570625_02475
Unannotated protein.
  
 0.989
GCA_001570625_00365
Unannotated protein.
  
  
 0.898
GCA_001570625_00366
Unannotated protein.
  
  
 0.883
GCA_001570625_00315
Unannotated protein.
  
  
 0.868
GCA_001570625_00181
Unannotated protein.
    
 
 0.805
GCA_001570625_00186
Unannotated protein.
    
 
 0.805
GCA_001570625_00367
Unannotated protein.
     
 0.799
fliE
Unannotated protein.
    
 
 0.798
GCA_001570625_00804
Unannotated protein.
  
  
 0.789
Your Current Organism:
Syntrophomonas wolfei methylbutyratica
NCBI taxonomy Id: 378794
Other names: CGMCC 1.5051, JCM 14075, S. wolfei subsp. methylbutyratica, Syntrophomonas wolfei subsp. methylbutyratica, strain 4J5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.