STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO74364.1ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (211 aa)    
Predicted Functional Partners:
ADO74363.1
Iron-sulfur cluster binding protein.
 
     0.755
metH
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.648
mutA
Methylmalonyl-CoA mutase, beta subunit.
 
   
 0.595
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
  
    0.587
thyA-2
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.581
mutB
Methylmalonyl-CoA mutase, alpha subunit.
 
   
 0.573
ADO72967.1
Ethanolamine ammonia-lyase, large subunit/small subunit.
 
   
 0.505
ADO70699.1
Sphingolipid C9-methyltransferase-like protein.
   
    0.482
ADO74581.1
LAO/AO transport system ATPase.
 
     0.409
Your Current Organism:
Stigmatella aurantiaca
NCBI taxonomy Id: 378806
Other names: S. aurantiaca DW4/3-1, Stigmatella aurantiaca DW4/3-1, Stigmatella aurantiaca str. DW4/3-1, Stigmatella aurantiaca strain DW4/3-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.