STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAU_0437Hypothetical protein. (313 aa)    
Predicted Functional Partners:
GAU_0438
Fumarylacetoacetase; Protein synonym: fumarylacetoacetate hydrolase.
 
     0.884
aspS
aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
  
  
 0.838
nadC
Nicotinate-nucleotide pyrophosphorylase (carboxylating); Protein synonym: QAPRTase; protein synonym: quinolinate phosphoribosyltransferase (decarboxylating); Belongs to the NadC/ModD family.
       0.777
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
 
 0.774
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
       0.773
GAU_1610
Hypothetical protein.
  
    0.762
GAU_2123
4-hydroxyphenylpyruvate dioxygenase; Protein synonym: 4HPPD; protein synonym: HPD; protein synonym: HPPDase.
 
     0.728
hmgA
Protein synonym: homogentisate oxygenase; protein synonym: homogentisic acid oxidase; protein synonym: homogentisicase.
 
     0.717
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.608
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.603
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
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