STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (531 aa)    
Predicted Functional Partners:
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU; Protein synonym: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase.
  
 0.997
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.990
cobO
cob(I)yrinic acid a,c-diamide adenosyltransferase; Protein synonym: cob(I)alamin adenosyltransferase; protein synonym: corrinoid adenosyltransferase.
  
 0.988
GAU_0490
Putative cob(I)yrinic acid a,c-diamide adenosyltransferase; Protein synonym: cob(I)alamin adenosyltransferase; protein synonym: corrinoid adenosyltransferase.
  
 0.983
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). Belongs to the phosphoglycerate mutase family.
 
  
 0.974
GAU_0491
Putative aminotransferase.
  
 0.935
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.926
GAU_0604
Hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family.
  
 
 0.922
GAU_1489
ABC transporter ATP-binding protein.
 
    0.829
GAU_0486
Phosphoglycerate mutase family.
 
  
 0.770
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
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