STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAU_1289Protein synonym: acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)    
Predicted Functional Partners:
GAU_2755
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase; Bifunctional protein.
 
 0.999
fadJ
enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Bifunctional protein.
 
 0.998
GAU_1291
3-hydroxyacyl-CoA dehydrogenase.
 0.987
paaH
Putative 3-hydroxybutyryl-CoA dehydrogenase.
 0.967
GAU_3272
acyl-CoA dehydrogenase.
  
 0.940
acsA
Putative acetoacetyl-CoA synthetase.
  
 
 0.930
GAU_2381
Putative 2-oxoglutarate ferredoxin-oxidoreductase alpha subunit.
  
 
 0.930
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.930
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 0.929
GAU_1782
acyl-CoA carboxylase alpha chain; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.920
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
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