STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbpFructose-1,6-bisphosphatase; Protein synonym: D-fructose-1,6-bisphosphate 1-phosphohydrolase. (360 aa)    
Predicted Functional Partners:
tkt
Transketolase; Protein synonym: TK; Belongs to the transketolase family.
  
 
 0.956
GAU_1107
Putative fructose-bisphosphate aldolase; Protein synonym: fructose-1,6-bisphosphate triosephosphate-lyase; protein synonym: ketose 1-phosphate aldolase.
 
 
 0.951
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.934
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.928
pgi
Glucose-6-phosphate isomerase; Protein synonym: GPI; protein synonym: PGI; protein synonym: PHI; protein synonym: phosphoglucose isomerase; protein synonym: phosphohexose isomerase; Belongs to the GPI family.
   
 
 0.927
GAU_1220
Putative sugar kinase.
     
 0.904
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
 
  
 0.745
idh
NADP-dependent isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
  
 0.627
GAU_1457
Putative isobutyryl-CoA mutase large subunit.
       0.561
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.538
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.