STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (393 aa)    
Predicted Functional Partners:
GAU_0558
Methylenetetrahydrofolate reductase family protein.
  
 0.988
cbs
Cystathionine beta-synthase; Protein synonym: beta-thionase; protein synonym: serine sulfhydrase.
 
 0.987
metX/hom
Homoserine O-acetyltransferase/homoserine dehydrogenase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the AB hydrolase superfamily. MetX family.
 
 0.964
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.963
cysK
Cysteine synthase A; Protein synonym: CSase; protein synonym: O-acetylserine (Thiol)-lyase; protein synonym: O-acetylserine sulfhydrylase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.949
GAU_2159
Cys/Met metabolism pyridoxal-phosphate-dependent enzyme.
  
  
 
0.924
cysD
Protein synonym: O-acetylhomoserine sulfhydrylase; protein synonym: OAH sulfhydrylase; protein synonym: homocysteine synthase.
 
 
0.923
GAU_2649
Putative hydrolase; Belongs to the AB hydrolase superfamily. MetX family.
 
  
 0.919
metB
Cystathionine gamma-synthase; Protein synonym: CGS.
  
  
 
0.917
GAU_1367
Aspartokinase/homoserine dehydrogenase; Bifunctional protein; protein synonym: AKI-HDI.
 
 
 0.915
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
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