node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KIE22119.1 | KIE22167.1 | SE23_04465 | SE23_01360 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.427 |
KIE22119.1 | clpA | SE23_04465 | SE23_13115 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Clp protease ClpX; ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. | 0.813 |
KIE22119.1 | clpB | SE23_04465 | SE23_07825 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.813 |
KIE22119.1 | grpE | SE23_04465 | SE23_02175 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.892 |
KIE22119.1 | hscA | SE23_04465 | SE23_01375 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.915 |
KIE22119.1 | htpG | SE23_04465 | SE23_12450 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.978 |
KIE22167.1 | KIE22119.1 | SE23_01360 | SE23_04465 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.427 |
KIE22167.1 | KIE22171.1 | SE23_01360 | SE23_01380 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
KIE22167.1 | KIE22172.1 | SE23_01360 | SE23_01385 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
KIE22167.1 | dnaJ | SE23_01360 | SE23_02190 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.518 |
KIE22167.1 | hscA | SE23_01360 | SE23_01375 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.981 |
KIE22167.1 | hscB | SE23_01360 | SE23_01370 | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cobalamin 5'-phosphate synthase; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.998 |
KIE22171.1 | KIE22167.1 | SE23_01380 | SE23_01360 | 2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.994 |
KIE22171.1 | KIE22172.1 | SE23_01380 | SE23_01385 | 2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
KIE22171.1 | hscA | SE23_01380 | SE23_01375 | 2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.975 |
KIE22171.1 | hscB | SE23_01380 | SE23_01370 | 2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin 5'-phosphate synthase; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.991 |
KIE22172.1 | KIE22167.1 | SE23_01385 | SE23_01360 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.904 |
KIE22172.1 | KIE22171.1 | SE23_01385 | SE23_01380 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
KIE22172.1 | hscA | SE23_01385 | SE23_01375 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.921 |
KIE22172.1 | hscB | SE23_01385 | SE23_01370 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin 5'-phosphate synthase; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.969 |