STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpRTrp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription. (99 aa)    
Predicted Functional Partners:
KIE20966.1
Lytic murein transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.795
matP
Ter macrodomain organizer matS-binding protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.741
KIE18717.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.693
KIE19335.1
Lysine transporter LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.639
KIE19754.1
DNA transformation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.636
KIE21179.1
DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
    0.591
mukF
Condesin subunit F; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
     0.590
KIE21039.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0231 family.
  
     0.586
KIE20969.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.572
mukE
Condesin subunit E; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.550
Your Current Organism:
Vibrio sinaloensis
NCBI taxonomy Id: 379097
Other names: CAIM 797, CECT 7298, V. sinaloensis, Vibrio sinaloensis Gomez-Gil et al. 2008, Vibrio sp. CAIM 695, Vibrio sp. CAIM 797
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.