STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KZO58804.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (287 aa)    
Predicted Functional Partners:
KZO58056.1
Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.993
KZO59083.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.991
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.981
folE
GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.887
KZO59082.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
0.859
KZO60581.1
4-amino-4-deoxychorismate lyase; Catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.831
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
   
 
 0.828
KZO60029.1
Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.788
KZO58761.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.712
KZO58760.1
Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.
       0.672
Your Current Organism:
Dietzia maris
NCBI taxonomy Id: 37915
Other names: ATCC 35013, AUCNM A-593, AUCNM:A:593, Brevibacterium maris, CCUG 44488, CIP 104188, D. maris, DSM 43672, IEGM 55, IFO 15801, IMV 195, JCM 6166, LMG 5361, LMG:5361, NBRC 15801, NRRL B-16941, NRRL:B:16941, Rhodococcus maris, VKM Ac-593, VKM:Ac:593
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