STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1283 aa)    
Predicted Functional Partners:
pdhD
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
mtr
Mycothione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
odhI_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.999
OIJ36810.1
Alpha-ketoacid dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
essC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.999
lpdA
NAD(P)H-quinone dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
merA_1
mercury(II) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
BK826_10285
Hypothetical protein; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.999
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.998
Your Current Organism:
Rothia kristinae
NCBI taxonomy Id: 37923
Other names: ATCC 27570, CCM 2690, CCUG 33026, CIP 81.69, DSM 20032, IEGM 390, IFO 15354, JCM 7237, Kocuria kristinae, Kocuria kristiniae, LMG 14215, LMG:14215, Micrococcus kristinae, Micrococcus kristiniae, NBRC 15354, NCTC 11038, NRRL B-14835, R. kristinae
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