STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ohrB_2Organic hydroperoxide resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)    
Predicted Functional Partners:
ohrR_2
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    0.851
ohrB_4
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.770
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
      
 0.698
otsA
Trehalose-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.685
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
      
 0.651
groS_2
Co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
      
 0.636
cspA
Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.613
OIJ36064.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.538
OIJ36133.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.482
curA
NADP-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.454
Your Current Organism:
Rothia kristinae
NCBI taxonomy Id: 37923
Other names: ATCC 27570, CCM 2690, CCUG 33026, CIP 81.69, DSM 20032, IEGM 390, IFO 15354, JCM 7237, Kocuria kristinae, Kocuria kristiniae, LMG 14215, LMG:14215, Micrococcus kristinae, Micrococcus kristiniae, NBRC 15354, NCTC 11038, NRRL B-14835, R. kristinae
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.