STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OIJ35380.1hydroxymethylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)    
Predicted Functional Partners:
pksG
hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
OIJ35458.1
Mevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.984
OIJ35383.1
Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.978
OIJ35382.1
Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.964
fni
Type 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
   
 0.937
menA_2
1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 
 0.839
mhpA_1
Phenol 2-monooxygenase; Catalyzes the formation of catechol from phenol; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.695
lipA_2
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
      0.658
guaB_3
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.555
OIJ35439.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.528
Your Current Organism:
Rothia kristinae
NCBI taxonomy Id: 37923
Other names: ATCC 27570, CCM 2690, CCUG 33026, CIP 81.69, DSM 20032, IEGM 390, IFO 15354, JCM 7237, Kocuria kristinae, Kocuria kristiniae, LMG 14215, LMG:14215, Micrococcus kristinae, Micrococcus kristiniae, NBRC 15354, NCTC 11038, NRRL B-14835, R. kristinae
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