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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
AMM31129.1HAD family hydrolase; Pfam:pfam13344 Haloacid dehalogenase-like hydrolase; Belongs to the HAD-like hydrolase superfamily. (276 aa)    
Predicted Functional Partners:
cmk
Pfam:pfam02224 Cytidylate kinase.
  
 
  0.928
purH
Bifunctional purine biosynthesis protein PurH; Pfam:pfam01808 AICARFT/IMPCHase bienzyme.
   
  0.920
AMM32419.1
Tat (Twin-arginine translocation) pathway signal sequence domain protein.
  
 
 0.914
AMM32274.1
Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Pfam:pfam13286 Phosphohydrolase-associated domain; Belongs to the dGTPase family. Type 2 subfamily.
   
 
  0.913
AMM32557.1
Pfam:pfam01156 Inosine-uridine preferring nucleoside hydrolase.
    
 0.910
AMM33170.1
Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
  0.908
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
  0.907
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
  0.907
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.907
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
  0.906
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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