Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMM31298.1Pfam:pfam03352 Methyladenine glycosylase. (198 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
      0.896
AMM31300.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
   
 0.859
AMM31297.1
DNA-3-methyladenine glycosylase ii; Pfam:pfam00730 HhH-GPD superfamily base excision DNA repair protein.
     
 0.829
AMM31299.1
DNA-N1-methyladenine dioxygenase; Pfam:pfam13532 2OG-Fe(II) oxygenase superfamily.
       0.811
AMM31301.1
RNA polymerase sigma factor, sigma-70 family; Pfam:pfam04542 Sigma-70 region 2; Belongs to the sigma-70 factor family.
       0.811
tadA
Cytidine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.610
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.529
AMM30991.1
Fe-S cluster assembly protein HesB; Pfam:pfam00730 HhH-GPD superfamily base excision DNA repair protein.
     
 0.419
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
    0.407
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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