STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)    
Predicted Functional Partners:
sucD
Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
AMM33234.1
2-oxoglutarate dehydrogenase, E1 subunit; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
 
 0.999
AMM32060.1
Succinate dehydrogenase; Pfam:pfam13085 2Fe-2S iron-sulfur cluster binding domain.
 
 0.990
AMM32061.1
Succinate dehydrogenase flavoprotein subunit; Pfam:pfam00890 FAD binding domain.
 
 0.987
AMM32063.1
Pfam:pfam01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit.
  
 
 0.985
AMM32062.1
Pfam:pfam01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit.
  
 
 0.984
AMM34447.1
PF06545 family protein; Pfam:pfam06545 Protein of unknown function (DUF1116).
  
 0.982
AMM31247.1
Pfam:pfam00463 Isocitrate lyase family.
   
 
 0.940
AMM32519.1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
 
 0.931
AMM30846.1
Catalytic domain of components of various dehydrogenase complexes; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
  
 0.930
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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