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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (196 aa)    
Predicted Functional Partners:
purH
Bifunctional purine biosynthesis protein PurH; Pfam:pfam01808 AICARFT/IMPCHase bienzyme.
  
 0.972
AMM34380.1
Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.972
AMM32195.1
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.954
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.949
AMM31883.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
  
 0.948
AMM32557.1
Pfam:pfam01156 Inosine-uridine preferring nucleoside hydrolase.
    
 0.938
AMM32491.1
Pfam:pfam02578 Multi-copper polyphenol oxidoreductase laccase.
    
  0.907
AMM31129.1
HAD family hydrolase; Pfam:pfam13344 Haloacid dehalogenase-like hydrolase; Belongs to the HAD-like hydrolase superfamily.
     
 0.902
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.875
hisF
Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 
 0.839
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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