STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMM32685.1Heat-shock protein Hsp20; Pfam:pfam00011 Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. (147 aa)    
Predicted Functional Partners:
AMM31329.1
ATPase; Pfam:pfam07724 AAA domain (Cdc48 subfamily); Belongs to the ClpA/ClpB family.
 
 
 0.683
clpB
Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.682
AMM30984.1
NDP-hexose 4-ketoreductase; Pfam:pfam07724 AAA domain (Cdc48 subfamily); Belongs to the ClpA/ClpB family.
  
 
 0.640
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.623
AMM32686.1
Pfam:pfam01756 Acyl-CoA oxidase.
 
    0.611
AMM32687.1
TetR family transcriptional regulator.
  
    0.564
grpE
Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.526
AMM32849.1
Phosphoribosyltransferase; Pfam:pfam12695 Alpha/beta hydrolase family.
 
  
 0.492
AMM30781.1
Acetyl-CoA carboxylase beta subunit; Pfam:pfam01039 Carboxyl transferase domain.
  
  
 0.442
AMM32688.1
Acetyl-CoA acyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.438
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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