STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMM33118.1Thioredoxin; Pfam:pfam00085 Thioredoxin. (150 aa)    
Predicted Functional Partners:
AMM34731.1
Thioredoxin reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.
 
 0.985
AMM31038.1
Flavoprotein; Pfam:pfam13738 Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.711
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.624
AMM34031.1
Chaperone protein; Pfam:pfam00226 DnaJ domain.
 
 
 0.575
grpE
Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
  
 0.568
AMM34039.1
Protein tyrosine phosphatase; Pfam:pfam01451 Low molecular weight phosphotyrosine protein phosphatase.
 
 
 0.565
AMM32196.1
Dihydrolipoamide dehydrogenase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.562
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 
 0.557
AMM32601.1
Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase.
   
 
 0.530
groS
Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 
 
 0.526
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.