AMM33570.1 protein (Sinomonas atrocyanea) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

AMM33570.1

Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein. (561 aa)

Predicted Functional Partners:

AMM31958.1

0.657

AMM33420.1

0.643

AMM30814.1

0.640

AMM34155.1

0.589

adc

0.560

AMM33862.1

0.559

AMM33229.1

0.529

AMM34093.1

0.529

AMM34081.1

0.517

AMM31782.1

0.478

Your Current Organism:

Sinomonas atrocyanea

NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMM30814.1	AMM31958.1	SA2016_0109	SA2016_1278	Uncharacterized membrane-anchored protein; Pfam:pfam03988 Repeat of Unknown Function (DUF347).	Pfam:pfam12587 Protein of unknown function (DUF3761).	0.407
AMM30814.1	AMM33570.1	SA2016_0109	SA2016_2905	Uncharacterized membrane-anchored protein; Pfam:pfam03988 Repeat of Unknown Function (DUF347).	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	0.640
AMM30814.1	AMM33862.1	SA2016_0109	SA2016_3198	Uncharacterized membrane-anchored protein; Pfam:pfam03988 Repeat of Unknown Function (DUF347).	Phospholipase C; Pfam:pfam04185 Phosphoesterase family.	0.622
AMM31782.1	AMM31958.1	SA2016_1100	SA2016_1278	Phospholipase; Pfam:pfam04185 Phosphoesterase family.	Pfam:pfam12587 Protein of unknown function (DUF3761).	0.556
AMM31782.1	AMM33570.1	SA2016_1100	SA2016_2905	Phospholipase; Pfam:pfam04185 Phosphoesterase family.	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	0.478
AMM31782.1	AMM33862.1	SA2016_1100	SA2016_3198	Phospholipase; Pfam:pfam04185 Phosphoesterase family.	Phospholipase C; Pfam:pfam04185 Phosphoesterase family.	0.929
AMM31958.1	AMM30814.1	SA2016_1278	SA2016_0109	Pfam:pfam12587 Protein of unknown function (DUF3761).	Uncharacterized membrane-anchored protein; Pfam:pfam03988 Repeat of Unknown Function (DUF347).	0.407
AMM31958.1	AMM31782.1	SA2016_1278	SA2016_1100	Pfam:pfam12587 Protein of unknown function (DUF3761).	Phospholipase; Pfam:pfam04185 Phosphoesterase family.	0.556
AMM31958.1	AMM33420.1	SA2016_1278	SA2016_2755	Pfam:pfam12587 Protein of unknown function (DUF3761).	Hypothetical protein; Pfam:pfam04185 Phosphoesterase family.	0.681
AMM31958.1	AMM33570.1	SA2016_1278	SA2016_2905	Pfam:pfam12587 Protein of unknown function (DUF3761).	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	0.657
AMM31958.1	AMM33862.1	SA2016_1278	SA2016_3198	Pfam:pfam12587 Protein of unknown function (DUF3761).	Phospholipase C; Pfam:pfam04185 Phosphoesterase family.	0.660
AMM33229.1	AMM33570.1	SA2016_2562	SA2016_2905	Putative ABC transporter permease protein; Pfam:pfam00950 ABC 3 transport family.	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	0.529
AMM33420.1	AMM31958.1	SA2016_2755	SA2016_1278	Hypothetical protein; Pfam:pfam04185 Phosphoesterase family.	Pfam:pfam12587 Protein of unknown function (DUF3761).	0.681
AMM33420.1	AMM33570.1	SA2016_2755	SA2016_2905	Hypothetical protein; Pfam:pfam04185 Phosphoesterase family.	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	0.643
AMM33420.1	AMM34081.1	SA2016_2755	SA2016_3420	Hypothetical protein; Pfam:pfam04185 Phosphoesterase family.	ABC transporter substrate-binding protein; Pfam:pfam09084 NMT1/THI5 like.	0.587
AMM33570.1	AMM30814.1	SA2016_2905	SA2016_0109	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	Uncharacterized membrane-anchored protein; Pfam:pfam03988 Repeat of Unknown Function (DUF347).	0.640
AMM33570.1	AMM31782.1	SA2016_2905	SA2016_1100	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	Phospholipase; Pfam:pfam04185 Phosphoesterase family.	0.478
AMM33570.1	AMM31958.1	SA2016_2905	SA2016_1278	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	Pfam:pfam12587 Protein of unknown function (DUF3761).	0.657
AMM33570.1	AMM33229.1	SA2016_2905	SA2016_2562	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	Putative ABC transporter permease protein; Pfam:pfam00950 ABC 3 transport family.	0.529
AMM33570.1	AMM33420.1	SA2016_2905	SA2016_2755	Manganese transporter; Pfam:pfam01566 Natural resistance-associated macrophage protein.	Hypothetical protein; Pfam:pfam04185 Phosphoesterase family.	0.643

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Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.46

expected number of edges:

10

PPI enrichment p-value:

1.13e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006396

RNA processing

6 of 91

1.7

2.37

1.24e-06

GO:0034470

ncRNA processing

5 of 75

1.7

2.06

1.40e-05

GO:0008033

tRNA processing

4 of 56

1.73

1.71

0.00017

GO:0009451

RNA modification

4 of 58

1.72

1.7

0.00017

GO:0006364

rRNA processing

3 of 21

2.03

1.67

0.00050

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003723

RNA binding

5 of 134

1.45

1.36

0.00040

GO:0140098

Catalytic activity, acting on RNA

5 of 154

1.39

1.3

0.00040

GO:0008649

rRNA methyltransferase activity

2 of 6

2.4

1.18

0.0068

GO:0051539

4 iron, 4 sulfur cluster binding

3 of 43

1.72

1.13

0.0049

GO:0000049

tRNA binding

2 of 25

1.78

0.8

0.0282

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1478

0.71

0.64

5.18e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2315

Mixed, incl. tRNA processing, and NusB family

4 of 21

2.16

2.28

3.19e-05

CL:2316

Mixed, incl. NusB family, and Methylthiotransferase

3 of 12

2.28

1.73

0.00053

CL:1849

Translation, and Ribosome biogenesis

5 of 142

1.42

1.3

0.00053

CL:2073

Mixed, incl. TGS-like, and RF-1 domain

2 of 6

2.4

1.02

0.0137

CL:2110

3-5 exonuclease, and S1 domain

2 of 8

2.28

0.94

0.0183

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

5 of 399

0.98

0.59

0.0210

GOCC:0005737

Cytoplasm

7 of 1152

0.66

0.43

0.0210

GOCC:0005622

Intracellular

9 of 1930

0.55

0.37

0.0210

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0698

rRNA processing

3 of 13

2.24

2.15

7.19e-05

KW-0949

S-adenosyl-L-methionine

4 of 52

1.76

1.89

6.65e-05

KW-0963

Cytoplasm

7 of 238

1.35

1.76

1.20e-06

KW-0819

tRNA processing

3 of 28

1.91

1.65

0.00043

KW-0004

4Fe-4S

3 of 39

1.76

1.46

0.00087

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007197

Radical SAM

3 of 24

1.97

1.06

0.0094

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00729

Elongator protein 3, MiaB family, Radical SAM

3 of 18

2.1

1.78

0.00034

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