STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (340 aa)    
Predicted Functional Partners:
AMM33899.1
AMP-dependent synthetase; Pfam:pfam00501 AMP-binding enzyme.
 
  0.987
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.945
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
   
 0.852
AMM33834.1
Membrane protein; Pfam:pfam13398 Peptidase M50B-like.
       0.773
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.729
AMM33828.1
Isochorismate synthase; Pfam:pfam00425 chorismate binding enzyme.
 
   
 0.689
AMM30807.1
L-Ala-D/L-Glu epimerase; Pfam:pfam02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain.
 
   
 0.600
AMM33835.1
Pfam:pfam01569 PAP2 superfamily.
       0.573
menG
Ubiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
     
 0.567
AMM33726.1
Folate-binding protein YgfZ; Pfam:pfam01571 Aminomethyltransferase folate-binding domain; Belongs to the GcvT family.
  
     0.413
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.