Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMM33944.1Sugar phosphate isomerase; Pfam:pfam01261 Xylose isomerase-like TIM barrel. (300 aa)    
Predicted Functional Partners:
AMM33945.1
Exopolyphosphatase; Pfam:pfam02541 Ppx/GppA phosphatase family.
       0.835
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.803
AMM33946.1
Pfam:pfam07179 SseB protein N-terminal domain.
       0.773
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.569
AMM33949.1
Methyltransferase family protein; Pfam:pfam05175 Methyltransferase small domain; Belongs to the methyltransferase superfamily.
 
     0.509
mca
Mycothiol S-conjugate amidase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
     0.481
AMM33948.1
Pfam:pfam01022 Bacterial regulatory protein, arsR family.
       0.474
AMM33180.1
Pfam:pfam04851 Type III restriction enzyme, res subunit.
  
     0.463
AMM31831.1
5-deoxyglucuronate isomerase; Pfam:pfam04962 KduI/IolB family.
  
  
 0.453
AMM30983.1
Pfam:pfam11774 Lsr2.
  
     0.421
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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