Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMM33996.1Pfam:pfam01274 Malate synthase; Belongs to the malate synthase family. (532 aa)    
Predicted Functional Partners:
AMM31247.1
Pfam:pfam00463 Isocitrate lyase family.
 
 0.999
AMM33858.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.968
AMM33995.1
Malate dehydrogenase; Pfam:pfam03949 Malic enzyme, NAD binding domain.
  
 
 0.961
AMM32429.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.947
AMM33398.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.947
AMM33234.1
2-oxoglutarate dehydrogenase, E1 subunit; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
   
 
 0.934
AMM31195.1
Acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 0.925
AMM31644.1
Acetyl-CoA synthetase (Acetate-CoA ligase); Pfam:pfam00501 AMP-binding enzyme.
   
 0.925
AMM32854.1
Acetyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme.
   
 0.925
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.925
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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