SDQ65943.1 protein (Arthrobacter crystallopoietes)

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Predicted Interactions

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Score

SDQ65943.1

Putative peptidoglycan lipid II flippase. (558 aa)

Predicted Functional Partners:

SDQ64935.1

0.962

SDQ65918.1

0.825

SDQ65485.1

0.809

SDQ65007.1

0.792

SDR12329.1

0.677

SDR18496.1

0.629

SDQ65841.1

0.619

SDQ30128.1

0.589

SDQ65992.1

0.582

murC

0.575

Your Current Organism:

Arthrobacter crystallopoietes

NCBI taxonomy Id: 37928
Other names: A. crystallopoietes, ATCC 15481, CIP 102717, DSM 20117, IFO 14235, JCM 2522, LMG 3819, LMG:3819, NBRC 14235

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDQ30128.1	SDQ65943.1	SAMN04489742_0526	SAMN04489742_2020	Polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP/exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.	Putative peptidoglycan lipid II flippase.	0.589
SDQ64935.1	SDQ65007.1	SAMN04489742_1978	SAMN04489742_1981	FHA domain-containing protein.	Cell division protein FtsW, lipid II flippase; Belongs to the SEDS family.	0.913
SDQ64935.1	SDQ65943.1	SAMN04489742_1978	SAMN04489742_2020	FHA domain-containing protein.	Putative peptidoglycan lipid II flippase.	0.962
SDQ65007.1	SDQ64935.1	SAMN04489742_1981	SAMN04489742_1978	Cell division protein FtsW, lipid II flippase; Belongs to the SEDS family.	FHA domain-containing protein.	0.913
SDQ65007.1	SDQ65943.1	SAMN04489742_1981	SAMN04489742_2020	Cell division protein FtsW, lipid II flippase; Belongs to the SEDS family.	Putative peptidoglycan lipid II flippase.	0.792
SDQ65007.1	SDQ65992.1	SAMN04489742_1981	SAMN04489742_2022	Cell division protein FtsW, lipid II flippase; Belongs to the SEDS family.	poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	0.410
SDQ65007.1	SDR18496.1	SAMN04489742_1981	SAMN04489742_4444	Cell division protein FtsW, lipid II flippase; Belongs to the SEDS family.	FHA domain-containing protein.	0.521
SDQ65007.1	murC	SAMN04489742_1981	SAMN04489742_4413	Cell division protein FtsW, lipid II flippase; Belongs to the SEDS family.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.804
SDQ65485.1	SDQ65943.1	SAMN04489742_2002	SAMN04489742_2020	Predicted nucleic acid-binding protein, contains Zn-ribbon domain (includes truncated derivatives).	Putative peptidoglycan lipid II flippase.	0.809
SDQ65485.1	SDR12329.1	SAMN04489742_2002	SAMN04489742_4071	Predicted nucleic acid-binding protein, contains Zn-ribbon domain (includes truncated derivatives).	DNA polymerase III, delta subunit.	0.667
SDQ65841.1	SDQ65918.1	SAMN04489742_2016	SAMN04489742_2019	N-acetylmuramoyl-L-alanine amidase.	Hypothetical protein.	0.437
SDQ65841.1	SDQ65943.1	SAMN04489742_2016	SAMN04489742_2020	N-acetylmuramoyl-L-alanine amidase.	Putative peptidoglycan lipid II flippase.	0.619
SDQ65841.1	SDQ65992.1	SAMN04489742_2016	SAMN04489742_2022	N-acetylmuramoyl-L-alanine amidase.	poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	0.520
SDQ65918.1	SDQ65841.1	SAMN04489742_2019	SAMN04489742_2016	Hypothetical protein.	N-acetylmuramoyl-L-alanine amidase.	0.437
SDQ65918.1	SDQ65943.1	SAMN04489742_2019	SAMN04489742_2020	Hypothetical protein.	Putative peptidoglycan lipid II flippase.	0.825
SDQ65943.1	SDQ30128.1	SAMN04489742_2020	SAMN04489742_0526	Putative peptidoglycan lipid II flippase.	Polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP/exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.	0.589
SDQ65943.1	SDQ64935.1	SAMN04489742_2020	SAMN04489742_1978	Putative peptidoglycan lipid II flippase.	FHA domain-containing protein.	0.962
SDQ65943.1	SDQ65007.1	SAMN04489742_2020	SAMN04489742_1981	Putative peptidoglycan lipid II flippase.	Cell division protein FtsW, lipid II flippase; Belongs to the SEDS family.	0.792
SDQ65943.1	SDQ65485.1	SAMN04489742_2020	SAMN04489742_2002	Putative peptidoglycan lipid II flippase.	Predicted nucleic acid-binding protein, contains Zn-ribbon domain (includes truncated derivatives).	0.809
SDQ65943.1	SDQ65841.1	SAMN04489742_2020	SAMN04489742_2016	Putative peptidoglycan lipid II flippase.	N-acetylmuramoyl-L-alanine amidase.	0.619

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Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.948

expected number of edges:

47

PPI enrichment p-value:

0.53

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000398

mRNA splicing, via spliceosome

7 of 229

1.81

3.04

2.77e-08

GO:0010467

Gene expression

9 of 1738

1.04

1.14

4.44e-06

GO:0022618

Ribonucleoprotein complex assembly

3 of 155

1.61

0.8

0.0239

GO:0000387

Spliceosomal snRNP assembly

2 of 30

2.15

0.75

0.0415

GO:0034641

Cellular nitrogen compound metabolic process

9 of 3050

0.79

0.67

0.00044

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1990935

Splicing factor binding

2 of 4

3.02

1.34

0.0038

GO:0003723

RNA binding

8 of 1208

1.14

1.24

2.24e-05

GO:0003676

Nucleic acid binding

9 of 3699

0.71

0.53

0.0038

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005686

U2 snRNP

5 of 20

2.72

5.12

1.89e-10

GO:0071011

Precatalytic spliceosome

6 of 53

2.38

4.86

1.24e-10

GO:0005684

U2-type spliceosomal complex

6 of 92

2.14

4.22

5.76e-10

GO:0071005

U2-type precatalytic spliceosome

5 of 48

2.34

4.12

5.07e-09

GO:0005681

Spliceosomal complex

7 of 176

1.92

3.93

1.89e-10

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:18986

U2 snRNP, and Nuclear cap binding complex

6 of 23

2.74

5.91

5.02e-12

CL:18988

U2 snRNP

4 of 12

2.84

4.05

3.05e-08

CL:19002

Splicing factor binding, and PSP, proline-rich

3 of 5

3.1

3.14

1.97e-06

CL:19016

U4 snRNP

2 of 5

2.92

1.53

0.0017

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03040

Spliceosome

7 of 266

1.74

3.21

1.84e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72165

mRNA Splicing - Minor Pathway

6 of 59

2.33

4.64

2.98e-10

MAP-72172

mRNA Splicing

7 of 296

1.7

2.88

1.45e-08

MAP-72203

Processing of Capped Intron-Containing Pre-mRNA

7 of 391

1.57

2.48

5.54e-08

MAP-8953854

Metabolism of RNA

9 of 946

1.3

1.91

1.45e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990904

Ribonucleoprotein complex

9 of 447

1.63

3.22

3.44e-11

GOCC:0097525

Spliceosomal snRNP complex

4 of 40

2.32

2.85

2.87e-06

GOCC:0005681

Spliceosomal complex

4 of 107

1.89

2.04

4.99e-05

GOCC:0005687

U4 snRNP

2 of 6

2.84

1.63

0.0011

GOCC:0005689

U12-type spliceosomal complex

2 of 8

2.72

1.53

0.0016

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0687

Ribonucleoprotein

4 of 93

1.96

2.16

3.14e-05

KW-0694

RNA-binding

4 of 347

1.38

1.06

0.0027

KW-0689

Ribosomal protein

2 of 63

1.82

0.7

0.0469

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