node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDQ33932.1 | SDR02679.1 | SAMN04489742_0714 | SAMN04489742_3563 | Membrane protein DedA, SNARE-associated domain. | Membrane protein DedA, SNARE-associated domain. | 0.684 |
SDQ44787.1 | SDR02679.1 | SAMN04489742_1152 | SAMN04489742_3563 | MFS transporter, DHA2 family, lincomycin resistance protein; Belongs to the major facilitator superfamily. | Membrane protein DedA, SNARE-associated domain. | 0.415 |
SDQ52686.1 | SDR02679.1 | SAMN04489742_1466 | SAMN04489742_3563 | Membrane protein DedA, SNARE-associated domain; Manually curated. | Membrane protein DedA, SNARE-associated domain. | 0.464 |
SDR02616.1 | SDR02661.1 | SAMN04489742_3560 | SAMN04489742_3562 | Ribonuclease BN, tRNA processing enzyme. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.769 |
SDR02616.1 | SDR02679.1 | SAMN04489742_3560 | SAMN04489742_3563 | Ribonuclease BN, tRNA processing enzyme. | Membrane protein DedA, SNARE-associated domain. | 0.503 |
SDR02616.1 | murI | SAMN04489742_3560 | SAMN04489742_3559 | Ribonuclease BN, tRNA processing enzyme. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.830 |
SDR02616.1 | rph | SAMN04489742_3560 | SAMN04489742_3561 | Ribonuclease BN, tRNA processing enzyme. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.797 |
SDR02661.1 | SDR02616.1 | SAMN04489742_3562 | SAMN04489742_3560 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease BN, tRNA processing enzyme. | 0.769 |
SDR02661.1 | SDR02679.1 | SAMN04489742_3562 | SAMN04489742_3563 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Membrane protein DedA, SNARE-associated domain. | 0.570 |
SDR02661.1 | murI | SAMN04489742_3562 | SAMN04489742_3559 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.976 |
SDR02661.1 | rph | SAMN04489742_3562 | SAMN04489742_3561 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.992 |
SDR02679.1 | SDQ33932.1 | SAMN04489742_3563 | SAMN04489742_0714 | Membrane protein DedA, SNARE-associated domain. | Membrane protein DedA, SNARE-associated domain. | 0.684 |
SDR02679.1 | SDQ44787.1 | SAMN04489742_3563 | SAMN04489742_1152 | Membrane protein DedA, SNARE-associated domain. | MFS transporter, DHA2 family, lincomycin resistance protein; Belongs to the major facilitator superfamily. | 0.415 |
SDR02679.1 | SDQ52686.1 | SAMN04489742_3563 | SAMN04489742_1466 | Membrane protein DedA, SNARE-associated domain. | Membrane protein DedA, SNARE-associated domain; Manually curated. | 0.464 |
SDR02679.1 | SDR02616.1 | SAMN04489742_3563 | SAMN04489742_3560 | Membrane protein DedA, SNARE-associated domain. | Ribonuclease BN, tRNA processing enzyme. | 0.503 |
SDR02679.1 | SDR02661.1 | SAMN04489742_3563 | SAMN04489742_3562 | Membrane protein DedA, SNARE-associated domain. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.570 |
SDR02679.1 | SDR03067.1 | SAMN04489742_3563 | SAMN04489742_3583 | Membrane protein DedA, SNARE-associated domain. | Major Facilitator Superfamily protein. | 0.430 |
SDR02679.1 | murI | SAMN04489742_3563 | SAMN04489742_3559 | Membrane protein DedA, SNARE-associated domain. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.578 |
SDR02679.1 | rph | SAMN04489742_3563 | SAMN04489742_3561 | Membrane protein DedA, SNARE-associated domain. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.563 |
SDR03067.1 | SDR02679.1 | SAMN04489742_3583 | SAMN04489742_3563 | Major Facilitator Superfamily protein. | Membrane protein DedA, SNARE-associated domain. | 0.430 |