STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDR10630.1Ribonucleoside-diphosphate reductase, class 1b, beta subunit. (434 aa)    
Predicted Functional Partners:
SDR10615.1
Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 0.999
nrdI
Protein involved in ribonucleotide reduction; Probably involved in ribonucleotide reductase function.
 
 
 0.997
SDR10568.1
Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit.
 
  
 0.972
cmk
Cytidylate kinase.
    
 0.927
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.924
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.915
tmk-2
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.915
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.914
SDQ72135.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.909
SDR16174.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.909
Your Current Organism:
Arthrobacter crystallopoietes
NCBI taxonomy Id: 37928
Other names: A. crystallopoietes, ATCC 15481, CIP 102717, DSM 20117, IFO 14235, JCM 2522, LMG 3819, LMG:3819, NBRC 14235
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