node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDQ63434.1 | panB | SAMN04489742_1917 | SAMN04489742_4396 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.785 |
SDQ63434.1 | panC | SAMN04489742_1917 | SAMN04489742_1912 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.849 |
SDQ81991.1 | panB | SAMN04489742_2695 | SAMN04489742_4396 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.932 |
SDQ81991.1 | panC | SAMN04489742_2695 | SAMN04489742_1912 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.935 |
SDR03371.1 | panB | SAMN04489742_3599 | SAMN04489742_4396 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.735 |
SDR03371.1 | panC | SAMN04489742_3599 | SAMN04489742_1912 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.602 |
SDR07470.1 | ilvD | SAMN04489742_3806 | SAMN04489742_3791 | Branched chain amino acid aminotransferase apoenzyme. | Dihydroxyacid dehydratase; Manually curated; Belongs to the IlvD/Edd family. | 0.978 |
SDR07470.1 | ilvE | SAMN04489742_3806 | SAMN04489742_2120 | Branched chain amino acid aminotransferase apoenzyme. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.927 |
SDR07470.1 | panB | SAMN04489742_3806 | SAMN04489742_4396 | Branched chain amino acid aminotransferase apoenzyme. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.912 |
ilvD | SDR07470.1 | SAMN04489742_3791 | SAMN04489742_3806 | Dihydroxyacid dehydratase; Manually curated; Belongs to the IlvD/Edd family. | Branched chain amino acid aminotransferase apoenzyme. | 0.978 |
ilvD | ilvE | SAMN04489742_3791 | SAMN04489742_2120 | Dihydroxyacid dehydratase; Manually curated; Belongs to the IlvD/Edd family. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.978 |
ilvD | panB | SAMN04489742_3791 | SAMN04489742_4396 | Dihydroxyacid dehydratase; Manually curated; Belongs to the IlvD/Edd family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.933 |
ilvE | SDR07470.1 | SAMN04489742_2120 | SAMN04489742_3806 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Branched chain amino acid aminotransferase apoenzyme. | 0.927 |
ilvE | ilvD | SAMN04489742_2120 | SAMN04489742_3791 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Dihydroxyacid dehydratase; Manually curated; Belongs to the IlvD/Edd family. | 0.978 |
ilvE | panB | SAMN04489742_2120 | SAMN04489742_4396 | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.912 |
pafA | panB | SAMN04489742_4136 | SAMN04489742_4396 | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.728 |
pafA | prcB | SAMN04489742_4136 | SAMN04489742_4138 | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | Proteasome endopeptidase complex, beta component Threonine peptidase. MEROPS family T01B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.982 |
panB | SDQ63434.1 | SAMN04489742_4396 | SAMN04489742_1917 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase. | 0.785 |
panB | SDQ81991.1 | SAMN04489742_4396 | SAMN04489742_2695 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.932 |
panB | SDR03371.1 | SAMN04489742_4396 | SAMN04489742_3599 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. | 0.735 |