node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFM48127.1 | SFM51334.1 | SAMN04487961_0417 | SAMN04487961_0535 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.982 |
SFM48127.1 | SFN07064.1 | SAMN04487961_0417 | SAMN04487961_2028 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.982 |
SFM48127.1 | gmk | SAMN04487961_0417 | SAMN04487961_0055 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.569 |
SFM48127.1 | ndk | SAMN04487961_0417 | SAMN04487961_2000 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.597 |
SFM48127.1 | tmk | SAMN04487961_0417 | SAMN04487961_1199 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.426 |
SFM51306.1 | SFM51334.1 | SAMN04487961_0534 | SAMN04487961_0535 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
SFM51306.1 | SFM76393.1 | SAMN04487961_0534 | SAMN04487961_1158 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.950 |
SFM51306.1 | SFN07064.1 | SAMN04487961_0534 | SAMN04487961_2028 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.999 |
SFM51306.1 | adk | SAMN04487961_0534 | SAMN04487961_2777 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.964 |
SFM51306.1 | cmk | SAMN04487961_0534 | SAMN04487961_2090 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Cytidylate kinase. | 0.967 |
SFM51306.1 | gmk | SAMN04487961_0534 | SAMN04487961_0055 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.958 |
SFM51306.1 | ndk | SAMN04487961_0534 | SAMN04487961_2000 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.961 |
SFM51306.1 | pyrH | SAMN04487961_0534 | SAMN04487961_2614 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.813 |
SFM51306.1 | tmk | SAMN04487961_0534 | SAMN04487961_1199 | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.967 |
SFM51334.1 | SFM48127.1 | SAMN04487961_0535 | SAMN04487961_0417 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | 0.982 |
SFM51334.1 | SFM51306.1 | SAMN04487961_0535 | SAMN04487961_0534 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.999 |
SFM51334.1 | SFM76393.1 | SAMN04487961_0535 | SAMN04487961_1158 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.943 |
SFM51334.1 | SFN07064.1 | SAMN04487961_0535 | SAMN04487961_2028 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.946 |
SFM51334.1 | adk | SAMN04487961_0535 | SAMN04487961_2777 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.959 |
SFM51334.1 | cmk | SAMN04487961_0535 | SAMN04487961_2090 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Cytidylate kinase. | 0.960 |