STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpmThiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. (217 aa)    
Predicted Functional Partners:
SFN25438.1
Calcineurin-like phosphoesterase.
   
   0.601
SFN27713.1
Calcineurin-like phosphoesterase.
   
   0.601
SFM98356.1
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
    0.554
SFM79433.1
Ca-activated chloride channel family protein.
  
 
 0.535
SFM79406.1
Protein of unknown function.
  
 
 0.462
mnmC
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.
    
 0.434
SFN47852.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
  
 0.419
SFM52981.1
Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family.
    
  0.410
SFM92308.1
Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family.
    
  0.410
ubiB
2-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
    
  0.410
Your Current Organism:
Marinobacter pelagius
NCBI taxonomy Id: 379482
Other names: CGMCC 1.6775, JCM 14804, M. pelagius, Marinobacter pelagius Xu et al. 2008, Marinobacter sp. HS225, strain HS225
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.