STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PXR1Protein PXR1; Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase; Belongs to the PINX1 family. (345 aa)    
Predicted Functional Partners:
LELG_02198
Pre-mRNA splicing factor ATP-dependent RNA helicase PRP43.
   
 
 0.972
LELG_00533
U3 small nucleolar RNA-associated protein 7.
   
   0.967
LELG_05129
Protein ENP1.
   
   0.965
LELG_05744
Fibrillarin.
   
   0.959
LELG_02649
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
   0.955
LELG_00289
MI domain-containing protein.
   
   0.953
LELG_01457
Uncharacterized protein.
   
 
 0.953
FAL1
ATP-dependent RNA helicase FAL1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity). Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
   
   0.952
LELG_04683
Uncharacterized protein.
   
   0.952
SQS1
Protein SQS1; May be involved in splicing; Belongs to the SQS1 family.
    
 
 0.947
Your Current Organism:
Lodderomyces elongisporus
NCBI taxonomy Id: 379508
Other names: L. elongisporus NRRL YB-4239, Lodderomyces elongisporus NRRL YB-4239
Server load: low (28%) [HD]