STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPL4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (600 aa)    
Predicted Functional Partners:
LELG_00389
Cell division control protein 48; Belongs to the AAA ATPase family.
   
 0.999
LELG_01085
Ubiquitin fusion degradation protein 1.
   
 0.999
LELG_00844
UBX domain-containing protein.
    
 0.998
LELG_03047
Uncharacterized protein.
   
 0.983
LELG_00478
Uncharacterized protein.
   
 
 0.979
LELG_03923
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 
 0.971
LELG_02846
U-box domain-containing protein.
    
 
 0.970
LELG_01621
OTU domain-containing protein.
    
 
 0.969
LELG_05742
UBX domain-containing protein.
    
 
 0.969
LELG_05253
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 
 0.966
Your Current Organism:
Lodderomyces elongisporus
NCBI taxonomy Id: 379508
Other names: L. elongisporus NRRL YB-4239, Lodderomyces elongisporus NRRL YB-4239
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