METTL3 protein (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

METTL3

Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)

Predicted Functional Partners:

WTAP

0.994

ERCC3

0.939

VIRMA

0.900

RBM15

0.857

NEU1

0.793

CBLL1

0.779

NCBP1

0.753

ENSPCOP00000027612

0.753

POLR2A

0.739

ENSPCOP00000003049

0.724

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBLL1	METTL3	ENSPCOP00000028309	ENSPCOP00000024391	Cbl proto-oncogene like 1.	Methyltransferase like 3; Belongs to the MT-A70-like family.	0.779
CBLL1	RBM15	ENSPCOP00000028309	ENSPCOP00000016019	Cbl proto-oncogene like 1.	RNA binding motif protein 15.	0.713
CBLL1	VIRMA	ENSPCOP00000028309	ENSPCOP00000013413	Cbl proto-oncogene like 1.	Vir like m6A methyltransferase associated.	0.976
CBLL1	WTAP	ENSPCOP00000028309	ENSPCOP00000006119	Cbl proto-oncogene like 1.	WT1 associated protein.	0.987
ENSPCOP00000003049	ENSPCOP00000027612	ENSPCOP00000003049	ENSPCOP00000027612	Uncharacterized protein.	Uncharacterized protein.	0.771
ENSPCOP00000003049	ERCC3	ENSPCOP00000003049	ENSPCOP00000025369	Uncharacterized protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.990
ENSPCOP00000003049	METTL3	ENSPCOP00000003049	ENSPCOP00000024391	Uncharacterized protein.	Methyltransferase like 3; Belongs to the MT-A70-like family.	0.724
ENSPCOP00000003049	NCBP1	ENSPCOP00000003049	ENSPCOP00000016512	Uncharacterized protein.	Nuclear cap binding protein subunit 1.	0.771
ENSPCOP00000003049	POLR2A	ENSPCOP00000003049	ENSPCOP00000025964	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
ENSPCOP00000003049	WTAP	ENSPCOP00000003049	ENSPCOP00000006119	Uncharacterized protein.	WT1 associated protein.	0.683
ENSPCOP00000027612	ENSPCOP00000003049	ENSPCOP00000027612	ENSPCOP00000003049	Uncharacterized protein.	Uncharacterized protein.	0.771
ENSPCOP00000027612	ERCC3	ENSPCOP00000027612	ENSPCOP00000025369	Uncharacterized protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.693
ENSPCOP00000027612	METTL3	ENSPCOP00000027612	ENSPCOP00000024391	Uncharacterized protein.	Methyltransferase like 3; Belongs to the MT-A70-like family.	0.753
ENSPCOP00000027612	NCBP1	ENSPCOP00000027612	ENSPCOP00000016512	Uncharacterized protein.	Nuclear cap binding protein subunit 1.	0.433
ENSPCOP00000027612	POLR2A	ENSPCOP00000027612	ENSPCOP00000025964	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.767
ERCC3	ENSPCOP00000003049	ENSPCOP00000025369	ENSPCOP00000003049	ERCC excision repair 3, TFIIH core complex helicase subunit.	Uncharacterized protein.	0.990
ERCC3	ENSPCOP00000027612	ENSPCOP00000025369	ENSPCOP00000027612	ERCC excision repair 3, TFIIH core complex helicase subunit.	Uncharacterized protein.	0.693
ERCC3	METTL3	ENSPCOP00000025369	ENSPCOP00000024391	ERCC excision repair 3, TFIIH core complex helicase subunit.	Methyltransferase like 3; Belongs to the MT-A70-like family.	0.939
ERCC3	NCBP1	ENSPCOP00000025369	ENSPCOP00000016512	ERCC excision repair 3, TFIIH core complex helicase subunit.	Nuclear cap binding protein subunit 1.	0.693
ERCC3	NEU1	ENSPCOP00000025369	ENSPCOP00000010638	ERCC excision repair 3, TFIIH core complex helicase subunit.	Neuraminidase 1.	0.898