STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNRD2Thioredoxin reductase 2. (520 aa)    
Predicted Functional Partners:
BCKDHB
Branched chain keto acid dehydrogenase E1 subunit beta.
  
 0.991
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.991
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.985
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.971
PDHX
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.970
DLAT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.964
ENSPCOP00000013221
2-oxoacid_dh domain-containing protein.
  
 0.963
DLST
Lipoyl-binding domain-containing protein.
  
 0.963
TXNDC8
Thioredoxin domain-containing protein.
  
 0.950
TXN
Thioredoxin domain-containing protein.
  
 0.949
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.