STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNIPThioredoxin interacting protein. (397 aa)    
Predicted Functional Partners:
TXN
Thioredoxin domain-containing protein.
    
 0.998
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.964
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
   0.951
TXN2
Thioredoxin 2.
    
 0.949
TXNDC8
Thioredoxin domain-containing protein.
    
 0.937
VAV2
Vav guanine nucleotide exchange factor 2.
    
   0.937
NLRP3
NLR family pyrin domain containing 3.
     
 0.933
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
   0.887
NME9
NME/NM23 family member 9.
    
 0.836
NME8
NME/NM23 family member 8.
    
 0.718
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.