STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXKTyrosine-protein kinase. (581 aa)    
Predicted Functional Partners:
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.921
LCP2
Lymphocyte cytosolic protein 2.
   
 0.917
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.903
VAV2
Vav guanine nucleotide exchange factor 2.
   
 0.897
ITK
Tyrosine-protein kinase.
  
 
 
0.887
PIK3R3
Uncharacterized protein.
    
 0.882
PIK3R2
Uncharacterized protein.
    
 0.882
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.882
PIK3CA
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 0.876
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 0.876
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (14%) [HD]