STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0Z10_g8766Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (156 aa)    
Predicted Functional Partners:
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
    
 
 0.938
E0Z10_g2446
Uncharacterized protein; Belongs to the BolA/IbaG family.
  
 
 0.889
E0Z10_g921
Uncharacterized protein; Belongs to the BolA/IbaG family.
  
 
 0.889
E0Z10_g5201
Uncharacterized protein; Belongs to the BolA/IbaG family.
  
 
 0.862
E0Z10_g1656
Fe-S_biosyn domain-containing protein.
  
 0.838
E0Z10_g656
Uncharacterized protein.
  
 0.806
E0Z10_g1841
ABC1 domain-containing protein.
   
  
 0.779
E0Z10_g10782
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
   
    0.775
E0Z10_g7493
U3 small nucleolar RNA-associated protein 22.
   
    0.775
E0Z10_g1887
Ribosomal_L2_C domain-containing protein.
   
    0.775
Your Current Organism:
Xylaria hypoxylon
NCBI taxonomy Id: 37992
Other names: X. hypoxylon
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.