E0Z10_g6291 protein (Xylaria hypoxylon) - STRING interaction network

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Score

E0Z10_g6291

Uncharacterized protein. (1758 aa)

Predicted Functional Partners:

E0Z10_g1045

0.974

E0Z10_g535

0.972

E0Z10_g216

0.969

E0Z10_g3237

0.960

E0Z10_g9846

0.941

E0Z10_g5877

0.936

E0Z10_g9286

0.932

E0Z10_g3911

0.929

E0Z10_g7330

0.929

E0Z10_g3415

0.924

Your Current Organism:

Xylaria hypoxylon

NCBI taxonomy Id: 37992
Other names: X. hypoxylon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0Z10_g1045	E0Z10_g216	A0A4Z0YUH6	A0A4Z0Z9J3	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein.	0.837
E0Z10_g1045	E0Z10_g3237	A0A4Z0YUH6	A0A4Z0YZX9	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	XPGI domain-containing protein.	0.853
E0Z10_g1045	E0Z10_g3415	A0A4Z0YUH6	A0A4Z0Z7I2	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.804
E0Z10_g1045	E0Z10_g3911	A0A4Z0YUH6	A0A4Z0YMB2	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	ERCC4 domain-containing protein.	0.921
E0Z10_g1045	E0Z10_g535	A0A4Z0YUH6	A0A4Z0Z7E0	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.921
E0Z10_g1045	E0Z10_g5877	A0A4Z0YUH6	A0A4Z0YTZ5	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein.	0.874
E0Z10_g1045	E0Z10_g6291	A0A4Z0YUH6	A0A4Z0YR54	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein.	0.974
E0Z10_g1045	E0Z10_g7330	A0A4Z0YUH6	A0A4Z0YN34	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.777
E0Z10_g1045	E0Z10_g9286	A0A4Z0YUH6	A0A4Z0YSP2	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	RECA_2 domain-containing protein.	0.876
E0Z10_g1045	E0Z10_g9846	A0A4Z0YUH6	A0A4Z0YMM3	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.987
E0Z10_g216	E0Z10_g1045	A0A4Z0Z9J3	A0A4Z0YUH6	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.837
E0Z10_g216	E0Z10_g3237	A0A4Z0Z9J3	A0A4Z0YZX9	Uncharacterized protein.	XPGI domain-containing protein.	0.692
E0Z10_g216	E0Z10_g3415	A0A4Z0Z9J3	A0A4Z0Z7I2	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.818
E0Z10_g216	E0Z10_g3911	A0A4Z0Z9J3	A0A4Z0YMB2	Uncharacterized protein.	ERCC4 domain-containing protein.	0.882
E0Z10_g216	E0Z10_g535	A0A4Z0Z9J3	A0A4Z0Z7E0	Uncharacterized protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.980
E0Z10_g216	E0Z10_g5877	A0A4Z0Z9J3	A0A4Z0YTZ5	Uncharacterized protein.	Uncharacterized protein.	0.947
E0Z10_g216	E0Z10_g6291	A0A4Z0Z9J3	A0A4Z0YR54	Uncharacterized protein.	Uncharacterized protein.	0.969
E0Z10_g216	E0Z10_g7330	A0A4Z0Z9J3	A0A4Z0YN34	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.764
E0Z10_g216	E0Z10_g9286	A0A4Z0Z9J3	A0A4Z0YSP2	Uncharacterized protein.	RECA_2 domain-containing protein.	0.955
E0Z10_g216	E0Z10_g9846	A0A4Z0Z9J3	A0A4Z0YMM3	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.662