STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0Z10_g2380Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1084 aa)    
Predicted Functional Partners:
E0Z10_g7350
Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
    
 0.996
E0Z10_g6852
Uncharacterized protein.
    
 0.991
E0Z10_g8470
Uncharacterized protein.
    
 
 0.977
E0Z10_g5680
Histone H3; Belongs to the histone H3 family.
    
 0.947
E0Z10_g6441
Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.939
E0Z10_g1559
Rtt106 domain-containing protein.
    
 
 0.934
E0Z10_g899
WD_REPEATS_REGION domain-containing protein.
    
 
 0.929
E0Z10_g4994
WD_REPEATS_REGION domain-containing protein.
    
 
 0.924
E0Z10_g8106
Uncharacterized protein.
    
 0.922
E0Z10_g5843
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
   0.910
Your Current Organism:
Xylaria hypoxylon
NCBI taxonomy Id: 37992
Other names: X. hypoxylon
Server load: medium (78%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.